Combinatorial entropy behaviour leads to range selective binding in ligand-receptor interactions

Multivalent ligand-receptor interactions enhance binding selectivity in biological systems, and may be exploited to design synthetic systems. Here the authors demonstrate a multivalent behavior where the ability to bind the target occurs when the receptor density is within a specific range.

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Autores principales: Meng Liu, Azzurra Apriceno, Miguel Sipin, Edoardo Scarpa, Laura Rodriguez-Arco, Alessandro Poma, Gabriele Marchello, Giuseppe Battaglia, Stefano Angioletti-Uberti
Formato: article
Lenguaje:EN
Publicado: Nature Portfolio 2020
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Acceso en línea:https://doaj.org/article/ae5f2342984c4fa3b96a0bc47482a97e
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