Gating mechanism of the extracellular entry to the lipid pathway in a TMEM16 scramblase
Some TMEM16 family members are Ca2+-dependent phospholipid scramblases, which also mediate non-selective ion transport; however, the mechanism how lipids permeate through the TMEM16 remains poorly understood. Here, the authors combine biochemical assays and simulations to identify the key steps regu...
Saved in:
| Main Authors: | , , , , , |
|---|---|
| Format: | article |
| Language: | EN |
| Published: |
Nature Portfolio
2018
|
| Subjects: | |
| Online Access: | https://doaj.org/article/ae6b3950bcc946ad841e6d949d6d90e5 |
| Tags: |
Add Tag
No Tags, Be the first to tag this record!
|