Immune-Mediated Systemic Vasculitis as the Proposed Cause of Sudden-Onset Sensorineural Hearing Loss following Lassa Virus Exposure in Cynomolgus Macaques

Immune-Mediated Systemic Vasculitis as the Proposed Cause of Sudden-Onset Sensorineural Hearing Loss following Lassa Virus Exposure in Cynomolgus Macaques

ABSTRACT Lassa virus (LASV) causes a severe, often fatal hemorrhagic disease in regions in Africa where the disease is endemic, and approximately 30% of patients develop sudden-onset sensorineural hearing loss after recovering from acute disease. The causal mechanism of hearing loss in LASV-infected...

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Autores principales: Kathleen A. Cashman, Eric R. Wilkinson, Xiankun Zeng, Anthony P. Cardile, Paul R. Facemire, Todd M. Bell, Jeremy J. Bearss, Carl I. Shaia, Connie S. Schmaljohn
Formato: article
Lenguaje:EN
Publicado: American Society for Microbiology 2018
Materias:
Lassa virus
Lassa fever
polyarteritis nodosa
microscopic polyangiitis
vasculitides
autoimmunity
Microbiology
QR1-502
Acceso en línea:https://doaj.org/article/ae9350fbdf8e4ad6afc4472d4595d22d
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https://doaj.org/article/ae9350fbdf8e4ad6afc4472d4595d22d

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