Environmental pH modulates inerolysin activity via post-binding blockade
Abstract The cholesterol dependent cytolysins (CDCs) are a family of pore-forming toxins produced by a wide range of bacteria. Some CDCs are important virulence factors for their cognate organisms, but their activity must be tightly regulated to ensure they operate at appropriate times and within th...
Saved in:
Main Authors: | Ryan Rampersaud, Emma L. Lewis, Timothy J. LaRocca, Adam J. Ratner |
---|---|
Format: | article |
Language: | EN |
Published: |
Nature Portfolio
2018
|
Subjects: | |
Online Access: | https://doaj.org/article/aea011bfef974b26a9bb104e9cc10ed8 |
Tags: |
Add Tag
No Tags, Be the first to tag this record!
|
Similar Items
-
Human-Specific Bacterial Pore-Forming Toxins Induce Programmed Necrosis in Erythrocytes
by: Timothy J. LaRocca, et al.
Published: (2014) -
Structural elements of a pH-sensitive inhibitor binding site in NMDA receptors
by: Michael C. Regan, et al.
Published: (2019) -
Reversible pH-controlled DNA-binding peptide nanotweezers: An in-silico study
by: Gaurav Sharma, et al.
Published: (2008) -
Influencing the adhesion properties and wettability of mucin protein films by variation of the environmental pH
by: Maria Sumarokova, et al.
Published: (2018) -
Redefining the specificity of phosphoinositide-binding by human PH domain-containing proteins
by: Nilmani Singh, et al.
Published: (2021)