UPF1/SMG7-dependent microRNA-mediated gene regulation
UPF1 mediates the decay of target mRNA in a 3′ untranslated region (UTR)-length-dependent manner. Here the authors reveal that the 3′UTR-length-dependent regulation of UPF1-dependent mRNA decay occurs through EJC-independent but miRNA-dependent regulation.
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Nature Portfolio
2019
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oai:doaj.org-article:aeabc36501bf4d86b4a07be8fc7af2cd2021-12-02T17:01:40ZUPF1/SMG7-dependent microRNA-mediated gene regulation10.1038/s41467-019-12123-72041-1723https://doaj.org/article/aeabc36501bf4d86b4a07be8fc7af2cd2019-09-01T00:00:00Zhttps://doi.org/10.1038/s41467-019-12123-7https://doaj.org/toc/2041-1723UPF1 mediates the decay of target mRNA in a 3′ untranslated region (UTR)-length-dependent manner. Here the authors reveal that the 3′UTR-length-dependent regulation of UPF1-dependent mRNA decay occurs through EJC-independent but miRNA-dependent regulation.Jungyun ParkJwa-Won SeoNarae AhnSeokju ParkJungwook HwangJin-Wu NamNature PortfolioarticleScienceQENNature Communications, Vol 10, Iss 1, Pp 1-15 (2019) |
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Science Q Jungyun Park Jwa-Won Seo Narae Ahn Seokju Park Jungwook Hwang Jin-Wu Nam UPF1/SMG7-dependent microRNA-mediated gene regulation |
description |
UPF1 mediates the decay of target mRNA in a 3′ untranslated region (UTR)-length-dependent manner. Here the authors reveal that the 3′UTR-length-dependent regulation of UPF1-dependent mRNA decay occurs through EJC-independent but miRNA-dependent regulation. |
format |
article |
author |
Jungyun Park Jwa-Won Seo Narae Ahn Seokju Park Jungwook Hwang Jin-Wu Nam |
author_facet |
Jungyun Park Jwa-Won Seo Narae Ahn Seokju Park Jungwook Hwang Jin-Wu Nam |
author_sort |
Jungyun Park |
title |
UPF1/SMG7-dependent microRNA-mediated gene regulation |
title_short |
UPF1/SMG7-dependent microRNA-mediated gene regulation |
title_full |
UPF1/SMG7-dependent microRNA-mediated gene regulation |
title_fullStr |
UPF1/SMG7-dependent microRNA-mediated gene regulation |
title_full_unstemmed |
UPF1/SMG7-dependent microRNA-mediated gene regulation |
title_sort |
upf1/smg7-dependent microrna-mediated gene regulation |
publisher |
Nature Portfolio |
publishDate |
2019 |
url |
https://doaj.org/article/aeabc36501bf4d86b4a07be8fc7af2cd |
work_keys_str_mv |
AT jungyunpark upf1smg7dependentmicrornamediatedgeneregulation AT jwawonseo upf1smg7dependentmicrornamediatedgeneregulation AT naraeahn upf1smg7dependentmicrornamediatedgeneregulation AT seokjupark upf1smg7dependentmicrornamediatedgeneregulation AT jungwookhwang upf1smg7dependentmicrornamediatedgeneregulation AT jinwunam upf1smg7dependentmicrornamediatedgeneregulation |
_version_ |
1718382104951128064 |