Delineating proinflammatory microenvironmental signals by ex vivo modeling of the immature intestinal stroma

Abstract The intestinal stroma provides an important microenvironment for immune cell activation. The perturbation of this tightly regulated process can lead to excessive inflammation. We know that upregulated Toll-like receptor 4 (TLR4) in the intestinal epithelium plays a key role in the inflammat...

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Auteurs principaux: Mari Ichinose, Nobumi Suzuki, Tongtong Wang, Josephine A. Wright, Tamsin R. M. Lannagan, Laura Vrbanac, Hiroki Kobayashi, Krystyna Gieniec, Jia Q. Ng, Souzaburo Ihara, Chris Mavrangelos, Yoku Hayakawa, Patrick Hughes, Daniel L. Worthley, Susan L. Woods
Format: article
Langue:EN
Publié: Nature Portfolio 2021
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Accès en ligne:https://doaj.org/article/aebf352fe0324c3cb4059278bf6e460e
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