PD-L1 upregulation is associated with activation of the DNA double-strand break repair pathway in patients with colitic cancer

PD-L1 upregulation is associated with activation of the DNA double-strand break repair pathway in patients with colitic cancer

Abstract Ulcerative colitis (UC) is a DNA damage-associated chronic inflammatory disease; the DNA double-strand break (DSB) repair pathway participates in UC-associated dysplasia/colitic cancer carcinogenesis. The DSB/interferon regulatory factor-1 (IRF-1) pathway can induce PD-L1 expression transcr...

Descripción completa

Guardado en:
Detalles Bibliográficos
Autores principales: Naoya Ozawa, Takehiko Yokobori, Katsuya Osone, Chika Katayama, Kunihiko Suga, Chika Komine, Yuta Shibasaki, Takuya Shiraishi, Takuhisa Okada, Ryuji Kato, Hiroomi Ogawa, Akihiko Sano, Makoto Sakai, Makoto Sohda, Hitoshi Ojima, Tatsuya Miyazaki, Yoko Motegi, Munenori Ide, Takashi Yao, Hiroyuki Kuwano, Ken Shirabe, Hiroshi Saeki
Formato: article
Lenguaje:EN
Publicado: Nature Portfolio 2021
Materias:
Medicine
R
Science
Q
Acceso en línea:https://doaj.org/article/af1b22a145e34167b4094d6666a0d50f
Etiquetas: Agregar Etiqueta
Sin Etiquetas, Sea el primero en etiquetar este registro!

Internet

https://doaj.org/article/af1b22a145e34167b4094d6666a0d50f

Ejemplares similares