GRK2 contributes to glucose mediated calcium responses and insulin secretion in pancreatic islet cells

Abstract Diabetes is a metabolic syndrome rooted in impaired insulin and/or glucagon secretory responses within the pancreatic islets of Langerhans (islets). Insulin secretion is primarily regulated by two key factors: glucose-mediated ATP production and G-protein coupled receptors (GPCRs) signaling...

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Autores principales: Jonathan Snyder, Atreju I Lackey, G. Schuyler Brown, Melisa Diaz, Tian Yuzhen, Priscila Y. Sato
Formato: article
Lenguaje:EN
Publicado: Nature Portfolio 2021
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Acceso en línea:https://doaj.org/article/af1b5d05e31540d9b993ae13c398778d
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