New Bioactive Fused Triazolothiadiazoles as Bcl-2-Targeted Anticancer Agents
A series of 3-(6-substituted phenyl-[1,2,4]-triazolo[3,4-b]-[1,3,4]-thiadiazol-3-yl)-1H-indoles (<b>5a</b>–<b>l</b>) were designed, synthesized and evaluated for anti-apoptotic Bcl-2-inhibitory activity. Synthesis of the target compounds was readily accomplished through a rea...
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Main Authors: | , , , , , , , |
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Format: | article |
Language: | EN |
Published: |
MDPI AG
2021
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Subjects: | |
Online Access: | https://doaj.org/article/af2a65ec3d3641878ea076cea3f09a8a |
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