A Shift in Paradigms: Spatial Genomics Approaches to Reveal Single-Cell Principles of Genome Organization
The genome tridimensional (3D) organization and its role towards the regulation of key cell processes such as transcription is currently a main question in biology. Interphase chromosomes are spatially segregated into “territories,” epigenetically-defined large domains of chromatin that interact to...
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Format: | article |
Langue: | EN |
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Frontiers Media S.A.
2021
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Accès en ligne: | https://doaj.org/article/af305b700cbb40f297ce41bae2185e13 |
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