Nanoassembly routes stimulate conflicting antibody quantity and quality for transmission-blocking malaria vaccines

Abstract Vaccine development efforts have recently focused on enabling strong immune responses to poorly immunogenic antigens, via display on multimerisation scaffolds or virus like particles (VLPs). Typically such studies demonstrate improved antibody titer comparing monomeric and nano-arrayed anti...

Full description

Saved in:
Bibliographic Details
Main Authors: Darren B. Leneghan, Kazutoyo Miura, Iona J. Taylor, Yuanyuan Li, Jing Jin, Karl D. Brune, Martin F. Bachmann, Mark Howarth, Carole A. Long, Sumi Biswas
Format: article
Language:EN
Published: Nature Portfolio 2017
Subjects:
R
Q
Online Access:https://doaj.org/article/af545a6db3a5422c9c7b0870d3c2cf54
Tags: Add Tag
No Tags, Be the first to tag this record!