Multi-functionality of a tryptophan residue conserved in substrate-binding groove of GH19 chitinases

Abstract GH19 and GH22 glycoside hydrolases belonging to the lysozyme superfamily have a related structure/function. A highly conserved tryptophan residue, Trp103, located in the binding groove of a GH19 chitinase from moss Bryum coronatum (BcChi-A) appears to have a function similar to that of well...

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Auteurs principaux: Takuya Nagata, Shoko Shinya, Takayuki Ohnuma, Tamo Fukamizo
Format: article
Langue:EN
Publié: Nature Portfolio 2021
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Accès en ligne:https://doaj.org/article/af857347caee45848bbbbf057bade540
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