Search for an association between V249I and T280M CX3CR1 genetic polymorphisms, endothelial injury and preeclampsia: the ECLAXIR study.

Search for an association between V249I and T280M CX3CR1 genetic polymorphisms, endothelial injury and preeclampsia: the ECLAXIR study.

<h4>Background</h4>Preeclampsia and coronary-artery disease share risk factors, suggesting common pathophysiological mechanisms. CX3CR1/CX3CL1 mediates leukocyte migration and adhesion and has been implicated in the pathophysiology of several inflammatory diseases. M280/I249 variants of...

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Main Authors: Alain Stepanian, Soraya Benchenni, Tiphaine Beillat-Lucas, Sophie Omnes, Fannie Defay, Edith Peynaud-Debayle, Gabriel Baron, Agnès Le Querrec, Michel Dreyfus, Laurence Salomon, Vassilis Tsatsaris, Dominique de Prost, Laurent Mandelbrot, ECLAXIR study group
Format: article
Language:EN
Published: Public Library of Science (PLoS) 2009
Subjects:
Medicine
R
Science
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Online Access:https://doaj.org/article/afc7d0bf34854e6daef6d618b7dd9645
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