Bardet-Biedl syndrome proteins modulate the release of bioactive extracellular vesicles

Extracellular vesicles (EV) are known to be released from the primary cilium, but the role ciliary proteins play in EV biogenesis remains unexplored. Here, the authors demonstrate increased secretion of small EVs with altered cargo composition from cells with known ciliarelated mutations. Wnt relate...

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Auteurs principaux: Ann-Kathrin Volz, Alina Frei, Viola Kretschmer, António M. de Jesus Domingues, Rene F. Ketting, Marius Ueffing, Karsten Boldt, Eva-Maria Krämer-Albers, Helen L. May-Simera
Format: article
Langue:EN
Publié: Nature Portfolio 2021
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Accès en ligne:https://doaj.org/article/b005eb92f5e343fd9d632f94442efafa
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