Levels of alpha-toxin correlate with distinct phenotypic response profiles of blood mononuclear cells and with agr background of community-associated Staphylococcus aureus isolates.

Levels of alpha-toxin correlate with distinct phenotypic response profiles of blood mononuclear cells and with agr background of community-associated Staphylococcus aureus isolates.

Epidemiological studies of Staphylococcus aureus have shown a relation between certain clones and the presence of specific virulence genes, but how this translates into virulence-associated functional responses is not fully elucidated. Here we addressed this issue by analyses of community-acquired S...

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Bibliographic Details
Main Authors: Srikanth Mairpady Shambat, Axana Haggar, Francois Vandenesch, Gerard Lina, Willem J B van Wamel, Gayathri Arakere, Mattias Svensson, Anna Norrby-Teglund
Format: article
Language:EN
Published: Public Library of Science (PLoS) 2014
Subjects:
Medicine
R
Science
Q
Online Access:https://doaj.org/article/b0090e8a5a8347598c5f8b0be5b8d68f
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