Antitumor effects of the small molecule DMAMCL in neuroblastoma via suppressing aerobic glycolysis and targeting PFKL

Abstract Background Neuroblastoma (NB) is a common solid malignancy in children that is associated with a poor prognosis. Although the novel small molecular compound Dimethylaminomicheliolide (DMAMCL) has been shown to induce cell death in some tumors, little is known about its role in NB. Methods W...

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Auteurs principaux: Simeng Zhang, Zhongyan Hua, Gen Ba, Ning Xu, Jianing Miao, Guifeng Zhao, Wei Gong, Zhihui Liu, Carol J. Thiele, Zhijie Li
Format: article
Langue:EN
Publié: BMC 2021
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Accès en ligne:https://doaj.org/article/b0095c6f2d3f473a86839c3944f6686b
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