Mining mutation contexts across the cancer genome to map tumor site of origin

The vast majority of somatic mutations observed in tumors are rare. Here, the authors show that these large numbers of rare mutations are more predictive of the tissue of origin of a tumor than the information from a few common driver mutations.

Guardado en:
Detalles Bibliográficos
Autores principales: Saptarshi Chakraborty, Axel Martin, Zoe Guan, Colin B. Begg, Ronglai Shen
Formato: article
Lenguaje:EN
Publicado: Nature Portfolio 2021
Materias:
Q
Acceso en línea:https://doaj.org/article/b01f12ed70af4a0e98b2eb41a7bf9303
Etiquetas: Agregar Etiqueta
Sin Etiquetas, Sea el primero en etiquetar este registro!