BiPOLES is an optogenetic tool developed for bidirectional dual-color control of neurons

BiPOLES is an optogenetic tool developed for bidirectional dual-color control of neurons

Currently, bidirectional control of activity in the same neurons in the same experiment is difficult. Here the authors report a Bidirectional Pair of Opsins for Light-induced Excitation and Silencing, BiPOLES, which they use in a range of organisms including worms, fruit flies, mice and ferrets.

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Auteurs principaux: Johannes Vierock, Silvia Rodriguez-Rozada, Alexander Dieter, Florian Pieper, Ruth Sims, Federico Tenedini, Amelie C. F. Bergs, Imane Bendifallah, Fangmin Zhou, Nadja Zeitzschel, Joachim Ahlbeck, Sandra Augustin, Kathrin Sauter, Eirini Papagiakoumou, Alexander Gottschalk, Peter Soba, Valentina Emiliani, Andreas K. Engel, Peter Hegemann, J. Simon Wiegert
Format: article
Langue:EN
Publié: Nature Portfolio 2021
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Science
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Accès en ligne:https://doaj.org/article/b02c3e09c1c84a398a03b09759bad1d1
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Internet

https://doaj.org/article/b02c3e09c1c84a398a03b09759bad1d1

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