Hybrid mass spectrometry approaches in glycoprotein analysis and their usage in scoring biosimilarity

Hybrid mass spectrometry approaches in glycoprotein analysis and their usage in scoring biosimilarity

Many biopharmaceuticals exhibit mixed heterogeneity in their post-translational modifications (PTMs) that are essential for their function. Here the authors use a combination of mass spectrometry techniques to analyse human erythropoietin (EPO) and properdin to discover new PTMs on properdin and der...

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Bibliographic Details
Main Authors: Yang Yang, Fan Liu, Vojtech Franc, Liem Andhyk Halim, Huub Schellekens, Albert J. R. Heck
Format: article
Language:EN
Published: Nature Portfolio 2016
Subjects:
Science
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Online Access:https://doaj.org/article/b02ee70614ff4f99a5c217410f8e376c
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