Kartogenin inhibits pain behavior, chondrocyte inflammation, and attenuates osteoarthritis progression in mice through induction of IL-10

Abstract Osteoarthritis (OA) is a major degenerative joint condition that causes articular cartilage destruction. It was recently found that enhancement of chondroclasts and suppression in Treg cell differentiation are involved in the pathogenesis of OA. Kartogenin (KGN) is a small drug-like molecul...

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Auteurs principaux: Ji Ye Kwon, Seung Hoon Lee, Hyun-Sik Na, KyungAh Jung, JeongWon Choi, Keun Hyung Cho, Chang-Yong Lee, Seok Jung Kim, Sung-Hwan Park, Dong-Yun Shin, Mi-La Cho
Format: article
Langue:EN
Publié: Nature Portfolio 2018
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Accès en ligne:https://doaj.org/article/b046e22e941d47cb8e63906a174a3d14
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