A CRISPR-based assay for the study of eukaryotic DNA repair onboard the International Space Station.

As we explore beyond Earth, astronauts may be at risk for harmful DNA damage caused by ionizing radiation. Double-strand breaks are a type of DNA damage that can be repaired by two major cellular pathways: non-homologous end joining, during which insertions or deletions may be added at the break sit...

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Bibliographic Details
Main Authors: Sarah Stahl-Rommel, David Li, Michelle Sung, Rebecca Li, Aarthi Vijayakumar, Kutay Deniz Atabay, G Guy Bushkin, Christian L Castro, Kevin D Foley, D Scott Copeland, Sarah L Castro-Wallace, Ezequiel Alvarez Saavedra, Emily J Gleason, Sebastian Kraves
Format: article
Language:EN
Published: Public Library of Science (PLoS) 2021
Subjects:
R
Q
Online Access:https://doaj.org/article/b05584a066a44f6ca8574d0d0e3317a4
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