Dissecting disease tolerance in Plasmodium vivax malaria using the systemic degree of inflammatory perturbation.

Homeostatic perturbation caused by infection fosters two major defense strategies, resistance and tolerance, which promote the host's survival. Resistance relates to the ability of the host to restrict the pathogen load. Tolerance minimizes collateral tissue damage without directly affecting pa...

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Main Authors: Caian L Vinhaes, Thomas A Carmo, Artur T L Queiroz, Kiyoshi F Fukutani, Mariana Araújo-Pereira, María B Arriaga, Marcus V G Lacerda, Manoel Barral-Netto, Bruno B Andrade
Format: article
Language:EN
Published: Public Library of Science (PLoS) 2021
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Online Access:https://doaj.org/article/b05dcac71d594064bdbb3ddd522c3c12
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