Specification of haematopoietic stem cell fate via modulation of mitochondrial activity
Haematopoietic stem cells rely on glycolysis for their energy demands but whether this affects their fate is unknown. Here, the authors show that forcing the cells to rely on glycolysis is important for self-renewal and that this involves a reduction in mitochondrial mass.
Saved in:
| Main Authors: | , , , , , , , , |
|---|---|
| Format: | article |
| Language: | EN |
| Published: |
Nature Portfolio
2016
|
| Subjects: | |
| Online Access: | https://doaj.org/article/b081f3f436004a1183c52fe48a38b2c1 |
| Tags: |
Add Tag
No Tags, Be the first to tag this record!
|