Predicting transcriptional activity of multiple site p53 mutants based on hybrid properties.

As an important tumor suppressor protein, reactivate mutated p53 was found in many kinds of human cancers and that restoring active p53 would lead to tumor regression. In this work, we developed a new computational method to predict the transcriptional activity for one-, two-, three- and four-site p...

Description complète

Enregistré dans:
Détails bibliographiques
Auteurs principaux: Tao Huang, Shen Niu, Zhongping Xu, Yun Huang, Xiangyin Kong, Yu-Dong Cai, Kuo-Chen Chou
Format: article
Langue:EN
Publié: Public Library of Science (PLoS) 2011
Sujets:
R
Q
Accès en ligne:https://doaj.org/article/b0939d94abdd4b6782539087cdd4a629
Tags: Ajouter un tag
Pas de tags, Soyez le premier à ajouter un tag!