Abundance of conserved CRISPR-Cas9 target sites within the highly polymorphic genomes of Anopheles and Aedes mosquitoes

Abundance of conserved CRISPR-Cas9 target sites within the highly polymorphic genomes of Anopheles and Aedes mosquitoes

Genetic variation in natural populations could represent gene drive resistant alleles, preventing successful application for population management. Here the authors survey 1280 genomes from three mosquito species and concludes natural variation will not be detrimental to deploying gene drive technol...

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Bibliographic Details
Main Authors: Hanno Schmidt, Travis C. Collier, Mark J. Hanemaaijer, Parker D. Houston, Yoosook Lee, Gregory C. Lanzaro
Format: article
Language:EN
Published: Nature Portfolio 2020
Subjects:
Science
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Online Access:https://doaj.org/article/b0a39060fec94d51a16902c1f33c8a06
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