Adjuvant Lineage-Negative Cell Therapy as a Potential Silencer of the Complement-Mediated Immune System in ALS Patients

Adjuvant Lineage-Negative Cell Therapy as a Potential Silencer of the Complement-Mediated Immune System in ALS Patients

ALS remains a fatal, neurodegenerative motor neuron disease. Numerous studies seem to confirm that innate immune system is involved in the pathophysiology of ALS. Hence, the assessment of the complement system and attempts to modify its activity remain the target of medical intervention in ALS. In t...

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Main Authors: Anna Sobuś, Bartłomiej Baumert, Monika Gołąb-Janowska, Piotr Kulig, Edyta Paczkowska, Karolina Łuczkowska, Dorota Rogińska, Alicja Zawiślak, Sławomir Milczarek, Bogumiła Osękowska, Wioletta Pawlukowska, Agnieszka Meller, Karolina Machowska-Sempruch, Agnieszka Wełnicka, Przemysław Nowacki, Bogusław Machaliński
Format: article
Language:EN
Published: MDPI AG 2021
Subjects:
amyotrophic lateral sclerosis
lineage-negative cells
cell therapy
innate immunity
complement system
Medicine
R
Online Access:https://doaj.org/article/b0ad234936694f92a088923edad79b3e
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https://doaj.org/article/b0ad234936694f92a088923edad79b3e

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