A quantitative model of cellular decision making in direct neuronal reprogramming

Abstract The direct reprogramming of adult skin fibroblasts to neurons is thought to be controlled by a small set of interacting gene regulators. Here, we investigate how the interaction dynamics between these regulating factors coordinate cellular decision making in direct neuronal reprogramming. W...

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Autores principales: Adriaan Merlevede, Emilie M. Legault, Viktor Drugge, Roger A. Barker, Janelle Drouin-Ouellet, Victor Olariu
Formato: article
Lenguaje:EN
Publicado: Nature Portfolio 2021
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Acceso en línea:https://doaj.org/article/b0ada2c304c64a60b053635df9de28ff
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