A quantitative model of cellular decision making in direct neuronal reprogramming
Abstract The direct reprogramming of adult skin fibroblasts to neurons is thought to be controlled by a small set of interacting gene regulators. Here, we investigate how the interaction dynamics between these regulating factors coordinate cellular decision making in direct neuronal reprogramming. W...
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Autores principales: | Adriaan Merlevede, Emilie M. Legault, Viktor Drugge, Roger A. Barker, Janelle Drouin-Ouellet, Victor Olariu |
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Formato: | article |
Lenguaje: | EN |
Publicado: |
Nature Portfolio
2021
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Materias: | |
Acceso en línea: | https://doaj.org/article/b0ada2c304c64a60b053635df9de28ff |
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