Inhibition of FOXO3 tumor suppressor function by betaTrCP1 through ubiquitin-mediated degradation in a tumor mouse model.

<h4>Background</h4>The ubiquitin-proteasome system is the primary proteolysis machine for controlling protein stability of the majority of regulatory proteins including those that are critical for cancer development. The forkhead box transcription factor FOXO3 plays a key role in regulat...

Descripción completa

Guardado en:
Detalles Bibliográficos
Autores principales: Wen-Bin Tsai, Young Min Chung, Yiyu Zou, See-Hyoung Park, Zhaohui Xu, Keiko Nakayama, Sue-Hwa Lin, Mickey C-T Hu
Formato: article
Lenguaje:EN
Publicado: Public Library of Science (PLoS) 2010
Materias:
R
Q
Acceso en línea:https://doaj.org/article/b0b03a58f4694d64a18c291c09a85f5e
Etiquetas: Agregar Etiqueta
Sin Etiquetas, Sea el primero en etiquetar este registro!