TRYPTOPHAN AND INDOLEAMINE-2,3-DIOXYGENASE (IDO) IN PATHOGENESIS OF IMMUNOSUPPRESSIVE CLINICAL CONDITIONS

Increasing amounts of literature data suggest the leading role of indoleamine 2,3-deoxygenase (IDO) enzyme in regulation of immunosuppressive mechanisms. IDO is produced, mostly, by dendritic cells, being induced, e.g., under IFNγ involvement. Its function is to provide catabolism of tryptophan, an...

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Autores principales: V. A. Kozlov, D. V. Demina
Formato: article
Lenguaje:RU
Publicado: SPb RAACI 2017
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Acceso en línea:https://doaj.org/article/b0dcc4ad92d94c48aafba6011501cf8a
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