TRYPTOPHAN AND INDOLEAMINE-2,3-DIOXYGENASE (IDO) IN PATHOGENESIS OF IMMUNOSUPPRESSIVE CLINICAL CONDITIONS
Increasing amounts of literature data suggest the leading role of indoleamine 2,3-deoxygenase (IDO) enzyme in regulation of immunosuppressive mechanisms. IDO is produced, mostly, by dendritic cells, being induced, e.g., under IFNγ involvement. Its function is to provide catabolism of tryptophan, an...
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| Main Authors: | , |
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| Format: | article |
| Language: | RU |
| Published: |
SPb RAACI
2017
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| Subjects: | |
| Online Access: | https://doaj.org/article/b0dcc4ad92d94c48aafba6011501cf8a |
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