Massively parallel RNA device engineering in mammalian cells with RNA-Seq
Synthetic RNA-based devices can dynamically control a wide range of processes. Here the authors develop a quantitative and high-throughput mammalian cell-based RNA-seq assay to efficiently engineer ribozyme switches.
Enregistré dans:
Auteurs principaux: | Joy S. Xiang, Matias Kaplan, Peter Dykstra, Michaela Hinks, Maureen McKeague, Christina D. Smolke |
---|---|
Format: | article |
Langue: | EN |
Publié: |
Nature Portfolio
2019
|
Sujets: | |
Accès en ligne: | https://doaj.org/article/b1085f5500c446be9254e89e2d3669c0 |
Tags: |
Ajouter un tag
Pas de tags, Soyez le premier à ajouter un tag!
|
Documents similaires
-
Massive mining of publicly available RNA-seq data from human and mouse
par: Alexander Lachmann, et autres
Publié: (2018) -
Unraveling the determinants of microRNA mediated regulation using a massively parallel reporter assay
par: Ilya Vainberg Slutskin, et autres
Publié: (2018) -
Single-nucleus RNA-seq and FISH identify coordinated transcriptional activity in mammalian myofibers
par: Matthieu Dos Santos, et autres
Publié: (2020) -
Engineering protein-protein devices for multilayered regulation of mRNA translation using orthogonal proteases in mammalian cells
par: Federica Cella, et autres
Publié: (2018) -
Protein-driven RNA nanostructured devices that function in vitro and control mammalian cell fate
par: Tomonori Shibata, et autres
Publié: (2017)