Src family kinases activity is required for transmitting purinergic P2X7 receptor signaling in cortical spreading depression and neuroinflammation

Highlights • SFKs activity-mediated P2X7 receptor signaling facilitates CSD propagation via glutamatergic pathway and also promotes neuroinflammation. • P2X7 receptor/SFKs signaling can be targeted for migraine prophylaxis and therapy.

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Autores principales: Lingdi Nie, Dongqing Ma, John P. Quinn, Minyan Wang
Formato: article
Lenguaje:EN
Publicado: BMC 2021
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R
Acceso en línea:https://doaj.org/article/b10f2349612542eea2abee1f3af21e42
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