Prediction and Biochemical Demonstration of a Catabolic Pathway for the Osmoprotectant Proline Betaine
ABSTRACT Through the use of genetic, enzymatic, metabolomic, and structural analyses, we have discovered the catabolic pathway for proline betaine, an osmoprotectant, in Paracoccus denitrificans and Rhodobacter sphaeroides. Genetic and enzymatic analyses showed that several of the key enzymes of the...
Saved in:
| Main Authors: | Ritesh Kumar, Suwen Zhao, Matthew W. Vetting, B. McKay Wood, Ayano Sakai, Kyuil Cho, José Solbiati, Steven C. Almo, Jonathan V. Sweedler, Matthew P. Jacobson, John A. Gerlt, John E. Cronan |
|---|---|
| Format: | article |
| Language: | EN |
| Published: |
American Society for Microbiology
2014
|
| Subjects: | |
| Online Access: | https://doaj.org/article/b13b4ca1a7f9489490ef07a83617a9d7 |
| Tags: |
Add Tag
No Tags, Be the first to tag this record!
|
Similar Items
-
Detection of drought tolerant sugarcane genotypes (Saccharum officinarum) using lipid peroxidation, antioxidant activity, glycine-betaine and proline contents
by: Abbas,S.R, et al.
Published: (2014) -
α-proteobacteria synthesize biotin precursor pimeloyl-ACP using BioZ 3-ketoacyl-ACP synthase and lysine catabolism
by: Yuanyuan Hu, et al.
Published: (2020) -
Lipid-containing osmoprotective eye drops in contact lens wearers
by: Aslan Bayhan S, et al.
Published: (2014) -
Combination of hyaluronic acid, carmellose, and osmoprotectants for the treatment of dry eye disease
by: Mateo Orobia AJ, et al.
Published: (2018) -
Utilization of genes encoding osmoprotectants in transgenic plants for enhanced abiotic stress tolerance
by: Khan,Mohammad Sayyar, et al.
Published: (2015)