Mechanistic basis of L-lactate transport in the SLC16 solute carrier family

The transport of L-lactate across plasma membranes is catalyzed by proton-driven monocarboxylate transporters (MCTs) of the SLC16 solute carrier family. Here, the authors present the crystal structures of a bacterial SLC16 homologue with the bound substrate L-lactate and ligand thiosalicylate both i...

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Auteurs principaux: Patrick D. Bosshart, David Kalbermatter, Sara Bonetti, Dimitrios Fotiadis
Format: article
Langue:EN
Publié: Nature Portfolio 2019
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Accès en ligne:https://doaj.org/article/b140603bfee541c0b8f279a225e59172
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