Mechanistic basis of L-lactate transport in the SLC16 solute carrier family
The transport of L-lactate across plasma membranes is catalyzed by proton-driven monocarboxylate transporters (MCTs) of the SLC16 solute carrier family. Here, the authors present the crystal structures of a bacterial SLC16 homologue with the bound substrate L-lactate and ligand thiosalicylate both i...
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Autores principales: | Patrick D. Bosshart, David Kalbermatter, Sara Bonetti, Dimitrios Fotiadis |
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Formato: | article |
Lenguaje: | EN |
Publicado: |
Nature Portfolio
2019
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Materias: | |
Acceso en línea: | https://doaj.org/article/b140603bfee541c0b8f279a225e59172 |
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