Lipopolysaccharide induces up-regulation of TGF-α through HDAC2 in a rat model of bronchopulmonary dysplasia.

Bronchopulmonary dysplasia (BPD) is characterized by alveolar simplification with decreased alveolar number and increased airspace. Previous studies suggested that transforming growth factor-α (TGF-α) may contribute to arrested alveolar development in BPD. Histone deacetylases (HDACs) control cellul...

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Auteurs principaux: Wensi Ni, Ning Lin, Hua He, Jianxing Zhu, Yongjun Zhang
Format: article
Langue:EN
Publié: Public Library of Science (PLoS) 2014
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R
Q
Accès en ligne:https://doaj.org/article/b14c010fd98e4c20942a9efd331d23af
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