Ecto-ADP-ribosyltransferase ARTC2.1 functionally modulates FcγR1 and FcγR2B on murine microglia

Ecto-ADP-ribosyltransferase ARTC2.1 functionally modulates FcγR1 and FcγR2B on murine microglia

Abstract Mammalian ecto-ADP-ribosyltransferases (ecto-ARTs or also ARTCs) catalyze the ADP-ribosylation of cell surface proteins using extracellular nicotinamide adenine dinucleotide (NAD+) as substrate. By this post-translational protein modification, ecto-ARTs modulate the function of various targ...

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Autores principales: Björn Rissiek, Stephan Menzel, Mario Leutert, Maike Cordes, Sarah Behr, Larissa Jank, Peter Ludewig, Mathias Gelderblom, Anne Rissiek, Sahil Adriouch, Friedrich Haag, Michael O. Hottiger, Friedrich Koch-Nolte, Tim Magnus
Formato: article
Lenguaje:EN
Publicado: Nature Portfolio 2017
Materias:
Medicine
R
Science
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Acceso en línea:https://doaj.org/article/b1ae8aec05a84e56935b6f2b9f614cd9
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https://doaj.org/article/b1ae8aec05a84e56935b6f2b9f614cd9

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