Contextual fear memory retrieval by correlated ensembles of ventral CA1 neurons
The vCA1-BA projection is enriched in shock responsive neurons, which are necessary for fear memory encoding and become correlated with a network of neurons during retrieval. Here the authors show that the magnitude of vCA1 correlated activity is proportional to memory strength and requires the shoc...
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oai:doaj.org-article:b1ae9cbb452a4a1cb40c60fdbc9c5b592021-12-02T16:08:14ZContextual fear memory retrieval by correlated ensembles of ventral CA1 neurons10.1038/s41467-020-17270-w2041-1723https://doaj.org/article/b1ae9cbb452a4a1cb40c60fdbc9c5b592020-07-01T00:00:00Zhttps://doi.org/10.1038/s41467-020-17270-whttps://doaj.org/toc/2041-1723The vCA1-BA projection is enriched in shock responsive neurons, which are necessary for fear memory encoding and become correlated with a network of neurons during retrieval. Here the authors show that the magnitude of vCA1 correlated activity is proportional to memory strength and requires the shock response during encoding.Jessica C. JimenezJack E. BerrySean C. LimSamantha K. OngMazen A. KheirbekRene HenNature PortfolioarticleScienceQENNature Communications, Vol 11, Iss 1, Pp 1-11 (2020) |
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Science Q Jessica C. Jimenez Jack E. Berry Sean C. Lim Samantha K. Ong Mazen A. Kheirbek Rene Hen Contextual fear memory retrieval by correlated ensembles of ventral CA1 neurons |
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The vCA1-BA projection is enriched in shock responsive neurons, which are necessary for fear memory encoding and become correlated with a network of neurons during retrieval. Here the authors show that the magnitude of vCA1 correlated activity is proportional to memory strength and requires the shock response during encoding. |
format |
article |
author |
Jessica C. Jimenez Jack E. Berry Sean C. Lim Samantha K. Ong Mazen A. Kheirbek Rene Hen |
author_facet |
Jessica C. Jimenez Jack E. Berry Sean C. Lim Samantha K. Ong Mazen A. Kheirbek Rene Hen |
author_sort |
Jessica C. Jimenez |
title |
Contextual fear memory retrieval by correlated ensembles of ventral CA1 neurons |
title_short |
Contextual fear memory retrieval by correlated ensembles of ventral CA1 neurons |
title_full |
Contextual fear memory retrieval by correlated ensembles of ventral CA1 neurons |
title_fullStr |
Contextual fear memory retrieval by correlated ensembles of ventral CA1 neurons |
title_full_unstemmed |
Contextual fear memory retrieval by correlated ensembles of ventral CA1 neurons |
title_sort |
contextual fear memory retrieval by correlated ensembles of ventral ca1 neurons |
publisher |
Nature Portfolio |
publishDate |
2020 |
url |
https://doaj.org/article/b1ae9cbb452a4a1cb40c60fdbc9c5b59 |
work_keys_str_mv |
AT jessicacjimenez contextualfearmemoryretrievalbycorrelatedensemblesofventralca1neurons AT jackeberry contextualfearmemoryretrievalbycorrelatedensemblesofventralca1neurons AT seanclim contextualfearmemoryretrievalbycorrelatedensemblesofventralca1neurons AT samanthakong contextualfearmemoryretrievalbycorrelatedensemblesofventralca1neurons AT mazenakheirbek contextualfearmemoryretrievalbycorrelatedensemblesofventralca1neurons AT renehen contextualfearmemoryretrievalbycorrelatedensemblesofventralca1neurons |
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1718384552562393088 |