New Pathogenesis Mechanisms and Translational Leads Identified by Multidimensional Analysis of Necrotizing Myositis in Primates

New Pathogenesis Mechanisms and Translational Leads Identified by Multidimensional Analysis of Necrotizing Myositis in Primates

ABSTRACT A fundamental goal of contemporary biomedical research is to understand the molecular basis of disease pathogenesis and exploit this information to develop targeted and more-effective therapies. Necrotizing myositis caused by the bacterial pathogen Streptococcus pyogenes is a devastating hu...

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Autores principales: Priyanka Kachroo, Jesus M. Eraso, Randall J. Olsen, Luchang Zhu, Samantha L. Kubiak, Layne Pruitt, Prasanti Yerramilli, Concepcion C. Cantu, Matthew Ojeda Saavedra, Johan Pensar, Jukka Corander, Leslie Jenkins, Lillian Kao, Alejandro Granillo, Adeline R. Porter, Frank R. DeLeo, James M. Musser
Formato: article
Lenguaje:EN
Publicado: American Society for Microbiology 2020
Materias:
bacterial pathogenesis
bacterial virulence
dual RNA-seq
necrotizing fasciitis
pathogen-host interaction
Streptococcus pyogenes
Microbiology
QR1-502
Acceso en línea:https://doaj.org/article/b1f2ba781c34426ea2c3cb8707edf5d5
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