5-Hydroxymethylcytosine localizes to enhancer elements and is associated with survival in glioblastoma patients

Glioblastomas have distorted epigenomes. Here, the authors compare the genome-wide profiles of 5-methylcytosine and 5- hydroxymethylcytosine in glioblastoma and prefrontal cortex tissue reporting a correlation between these profiles and patients’ prognosis.

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Auteurs principaux: Kevin C. Johnson, E. Andres Houseman, Jessica E. King, Katharine M. von Herrmann, Camilo E. Fadul, Brock C. Christensen
Format: article
Langue:EN
Publié: Nature Portfolio 2016
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Accès en ligne:https://doaj.org/article/b1fd49e9a254447bbb77068bd2d41e2b
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