5-Hydroxymethylcytosine localizes to enhancer elements and is associated with survival in glioblastoma patients
Glioblastomas have distorted epigenomes. Here, the authors compare the genome-wide profiles of 5-methylcytosine and 5- hydroxymethylcytosine in glioblastoma and prefrontal cortex tissue reporting a correlation between these profiles and patients’ prognosis.
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Auteurs principaux: | Kevin C. Johnson, E. Andres Houseman, Jessica E. King, Katharine M. von Herrmann, Camilo E. Fadul, Brock C. Christensen |
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Format: | article |
Langue: | EN |
Publié: |
Nature Portfolio
2016
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Accès en ligne: | https://doaj.org/article/b1fd49e9a254447bbb77068bd2d41e2b |
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