5-Hydroxymethylcytosine localizes to enhancer elements and is associated with survival in glioblastoma patients

Glioblastomas have distorted epigenomes. Here, the authors compare the genome-wide profiles of 5-methylcytosine and 5- hydroxymethylcytosine in glioblastoma and prefrontal cortex tissue reporting a correlation between these profiles and patients’ prognosis.

Guardado en:
Detalles Bibliográficos
Autores principales: Kevin C. Johnson, E. Andres Houseman, Jessica E. King, Katharine M. von Herrmann, Camilo E. Fadul, Brock C. Christensen
Formato: article
Lenguaje:EN
Publicado: Nature Portfolio 2016
Materias:
Q
Acceso en línea:https://doaj.org/article/b1fd49e9a254447bbb77068bd2d41e2b
Etiquetas: Agregar Etiqueta
Sin Etiquetas, Sea el primero en etiquetar este registro!