The mitochondrial iron transporter ABCB7 is required for B cell development, proliferation, and class switch recombination in mice
Iron-sulfur (Fe-S) clusters are cofactors essential for the activity of numerous enzymes including DNA polymerases, helicases, and glycosylases. They are synthesized in the mitochondria as Fe-S intermediates and are exported to the cytoplasm for maturation by the mitochondrial transporter ABCB7. Her...
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| Auteurs principaux: | , , , , , , |
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| Format: | article |
| Langue: | EN |
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eLife Sciences Publications Ltd
2021
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| Accès en ligne: | https://doaj.org/article/b26e13f1acd846d4bac1d67398df6ccb |
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