The art of using t-SNE for single-cell transcriptomics

t-SNE is widely used for dimensionality reduction and visualization of high-dimensional single-cell data. Here, the authors introduce a protocol to help avoid common shortcomings of t-SNE, for example, enabling preservation of the global structure of the data.

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Autores principales: Dmitry Kobak, Philipp Berens
Formato: article
Lenguaje:EN
Publicado: Nature Portfolio 2019
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Acceso en línea:https://doaj.org/article/b26f011209eb4d4294d5ab8dd1fde844
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spelling oai:doaj.org-article:b26f011209eb4d4294d5ab8dd1fde8442021-12-02T16:58:01ZThe art of using t-SNE for single-cell transcriptomics10.1038/s41467-019-13056-x2041-1723https://doaj.org/article/b26f011209eb4d4294d5ab8dd1fde8442019-11-01T00:00:00Zhttps://doi.org/10.1038/s41467-019-13056-xhttps://doaj.org/toc/2041-1723t-SNE is widely used for dimensionality reduction and visualization of high-dimensional single-cell data. Here, the authors introduce a protocol to help avoid common shortcomings of t-SNE, for example, enabling preservation of the global structure of the data.Dmitry KobakPhilipp BerensNature PortfolioarticleScienceQENNature Communications, Vol 10, Iss 1, Pp 1-14 (2019)
institution DOAJ
collection DOAJ
language EN
topic Science
Q
spellingShingle Science
Q
Dmitry Kobak
Philipp Berens
The art of using t-SNE for single-cell transcriptomics
description t-SNE is widely used for dimensionality reduction and visualization of high-dimensional single-cell data. Here, the authors introduce a protocol to help avoid common shortcomings of t-SNE, for example, enabling preservation of the global structure of the data.
format article
author Dmitry Kobak
Philipp Berens
author_facet Dmitry Kobak
Philipp Berens
author_sort Dmitry Kobak
title The art of using t-SNE for single-cell transcriptomics
title_short The art of using t-SNE for single-cell transcriptomics
title_full The art of using t-SNE for single-cell transcriptomics
title_fullStr The art of using t-SNE for single-cell transcriptomics
title_full_unstemmed The art of using t-SNE for single-cell transcriptomics
title_sort art of using t-sne for single-cell transcriptomics
publisher Nature Portfolio
publishDate 2019
url https://doaj.org/article/b26f011209eb4d4294d5ab8dd1fde844
work_keys_str_mv AT dmitrykobak theartofusingtsneforsinglecelltranscriptomics
AT philippberens theartofusingtsneforsinglecelltranscriptomics
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