The art of using t-SNE for single-cell transcriptomics
t-SNE is widely used for dimensionality reduction and visualization of high-dimensional single-cell data. Here, the authors introduce a protocol to help avoid common shortcomings of t-SNE, for example, enabling preservation of the global structure of the data.
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Nature Portfolio
2019
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oai:doaj.org-article:b26f011209eb4d4294d5ab8dd1fde8442021-12-02T16:58:01ZThe art of using t-SNE for single-cell transcriptomics10.1038/s41467-019-13056-x2041-1723https://doaj.org/article/b26f011209eb4d4294d5ab8dd1fde8442019-11-01T00:00:00Zhttps://doi.org/10.1038/s41467-019-13056-xhttps://doaj.org/toc/2041-1723t-SNE is widely used for dimensionality reduction and visualization of high-dimensional single-cell data. Here, the authors introduce a protocol to help avoid common shortcomings of t-SNE, for example, enabling preservation of the global structure of the data.Dmitry KobakPhilipp BerensNature PortfolioarticleScienceQENNature Communications, Vol 10, Iss 1, Pp 1-14 (2019) |
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Science Q Dmitry Kobak Philipp Berens The art of using t-SNE for single-cell transcriptomics |
description |
t-SNE is widely used for dimensionality reduction and visualization of high-dimensional single-cell data. Here, the authors introduce a protocol to help avoid common shortcomings of t-SNE, for example, enabling preservation of the global structure of the data. |
format |
article |
author |
Dmitry Kobak Philipp Berens |
author_facet |
Dmitry Kobak Philipp Berens |
author_sort |
Dmitry Kobak |
title |
The art of using t-SNE for single-cell transcriptomics |
title_short |
The art of using t-SNE for single-cell transcriptomics |
title_full |
The art of using t-SNE for single-cell transcriptomics |
title_fullStr |
The art of using t-SNE for single-cell transcriptomics |
title_full_unstemmed |
The art of using t-SNE for single-cell transcriptomics |
title_sort |
art of using t-sne for single-cell transcriptomics |
publisher |
Nature Portfolio |
publishDate |
2019 |
url |
https://doaj.org/article/b26f011209eb4d4294d5ab8dd1fde844 |
work_keys_str_mv |
AT dmitrykobak theartofusingtsneforsinglecelltranscriptomics AT philippberens theartofusingtsneforsinglecelltranscriptomics AT dmitrykobak artofusingtsneforsinglecelltranscriptomics AT philippberens artofusingtsneforsinglecelltranscriptomics |
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1718382409795239936 |