RIF1 Links Replication Timing with Fork Reactivation and DNA Double-Strand Break Repair

Replication timing (RT) is a cellular program to coordinate initiation of DNA replication in all origins within the genome. RIF1 (replication timing regulatory factor 1) is a master regulator of RT in human cells. This role of RIF1 is associated with binding G4-quadruplexes and changes in 3D chromat...

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Autores principales: Janusz Blasiak, Joanna Szczepańska, Anna Sobczuk, Michal Fila, Elzbieta Pawlowska
Formato: article
Lenguaje:EN
Publicado: MDPI AG 2021
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Acceso en línea:https://doaj.org/article/b2a85a44d92d472fa1e093dd9c039dc1
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