Curcumin derivative 1, 2-bis [(3E, 5E)-3, 5-bis [(2-chlorophenyl) methylene]-4-oxo-1-piperidyl] ethane-1, 2-dione (ST03) induces mitochondria mediated apoptosis in ovarian cancer cells and inhibits tumor progression in EAC mouse model
Curcumin is known for its anticancer properties, but its clinical application is limited due to its poor bioavailability and chemical stability. In this study we report the curcumin derivative, ST03 (1,2-bis[(3E,5E)-3,5-bis[(2-chlorophenyl)methylene]-4-oxo-1-piperidyl]ethane-1,2-dione) exhibits ∼ 14...
Saved in:
Main Authors: | Jinsha Koroth, Raghunandan Mahadeva, Febina Ravindran, Tanvi R Parashar, Vinay Teja, Subhas S Karki, Bibha Choudhary |
---|---|
Format: | article |
Language: | EN |
Published: |
Elsevier
2022
|
Subjects: | |
Online Access: | https://doaj.org/article/b2fe654f1f5b4ef0a1c015dfc2ae915f |
Tags: |
Add Tag
No Tags, Be the first to tag this record!
|
Similar Items
-
EXPERIMENTAL AND THEORETICAL ANALYSIS OF N,N’-(ETHANE-1,2-DIYLBIS(4,1-PHENYLENE))BIS(1-(THIOPHEN-2-YL)METHANIMINE) AND N,N’-(ETHANE-1,2-DIYLBIS(4,1-PHENYLENE))BIS(1-(4-METHYLTHIOPHEN-2-YL)METHANIMINE) SCHIFF BASE LIGANDS
by: Ulucam,Guhergul, et al.
Published: (2019) -
Curcumin derivative ST09 modulates the miR-199a-5p/DDR1 axis and regulates proliferation and migration in ovarian cancer cells
by: Febina Ravindran, et al.
Published: (2021) -
Bis(μ-cobaltoceniumselenolate-1:2κ2Se:Se)bis[bis(cobaltoceniumselenolate-κSe)mercury(II)] tetrakis(hexafluoridophosphate) acetonitrile disolvate
by: Daniel Menia, et al.
Published: (2021) -
NEW OPTICALLY ACTIVE ORGANO-SOLUBLE POLY(AMIDE-IMIDE)S FROM [N,N'-(4,4'-DIPHTALOYL)-BIS-L-AMINO DIACID]S AND 1,2-BIS[4,4'-AMINOPHENOXY] ETHANE: SYNTHESIS AND CHARACTERIZATION
by: FEYZI,AKRAM, et al.
Published: (2013) -
μ-BENZENE-1,2,4,5-TETRACARBOXYLATO-κ2O1:O4)BIS-[AQUA-BIS-2-(AMINOMETHYL) PYRIDINE-κ2N,N’) NICKEL (II)] DECAHYDRATE: STRUCTURE AND MAGNETIC PROPERTIES
by: Atria,Ana María, et al.
Published: (2019)