Global ubiquitination analysis reveals extensive modification and proteasomal degradation of cowpox virus proteins, but preservation of viral cores
Abstract The emergence of Variola virus-like viruses by natural evolution of zoonotic Orthopoxviruses, like Cowpox virus (CPXV), is a global health threat. The proteasome is essential for poxvirus replication, making the viral components interacting with the ubiquitin-proteasome system attractive an...
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Autores principales: | , , , , , , |
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Formato: | article |
Lenguaje: | EN |
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Nature Portfolio
2018
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Acceso en línea: | https://doaj.org/article/b316241190064730b98d479e44fbe6e2 |
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