On the heat stability of amyloid-based biological activity: insights from thermal degradation of insulin fibrils.

Formation of amyloid fibrils in vivo has been linked to disorders such as Alzheimer's disease and prion-associated transmissible spongiform encephalopathies. One of the characteristic features of amyloid fibrils is the high thermodynamic stability relative both to native and disordered states w...

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Autores principales: Weronika Surmacz-Chwedoruk, Iwona Malka, Łukasz Bożycki, Hanna Nieznańska, Wojciech Dzwolak
Formato: article
Lenguaje:EN
Publicado: Public Library of Science (PLoS) 2014
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Acceso en línea:https://doaj.org/article/b31ee8b3fde1447ebeefd06a43bea34e
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