Disordered flanks prevent peptide aggregation.

Natively unstructured or disordered regions appear to be abundant in eukaryotic proteins. Many such regions have been found alongside small linear binding motifs. We report a Monte Carlo study that aims to elucidate the role of disordered regions adjacent to such binding motifs. The coarse-grained s...

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Bibliographic Details
Main Authors: Sanne Abeln, Daan Frenkel
Format: article
Language:EN
Published: Public Library of Science (PLoS) 2008
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Online Access:https://doaj.org/article/b329eb55103644ce8989b2e9a27c9e01
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